81 research outputs found

    A Locality-based Neural Solver for Optical Motion Capture

    Full text link
    We present a novel locality-based learning method for cleaning and solving optical motion capture data. Given noisy marker data, we propose a new heterogeneous graph neural network which treats markers and joints as different types of nodes, and uses graph convolution operations to extract the local features of markers and joints and transform them to clean motions. To deal with anomaly markers (e.g. occluded or with big tracking errors), the key insight is that a marker's motion shows strong correlations with the motions of its immediate neighboring markers but less so with other markers, a.k.a. locality, which enables us to efficiently fill missing markers (e.g. due to occlusion). Additionally, we also identify marker outliers due to tracking errors by investigating their acceleration profiles. Finally, we propose a training regime based on representation learning and data augmentation, by training the model on data with masking. The masking schemes aim to mimic the occluded and noisy markers often observed in the real data. Finally, we show that our method achieves high accuracy on multiple metrics across various datasets. Extensive comparison shows our method outperforms state-of-the-art methods in terms of prediction accuracy of occluded marker position error by approximately 20%, which leads to a further error reduction on the reconstructed joint rotations and positions by 30%. The code and data for this paper are available at https://github.com/non-void/LocalMoCap.Comment: Siggraph Asia 2023 Conference Pape

    Endurance exercise accelerates myocardial tissue oxygenation recovery and reduces ischemia reperfusion injury in mice

    Get PDF
    Exercise training offers cardioprotection against ischemia and reperfusion (I/R) injury. However, few essential signals have been identified to underscore the protection from injury. In the present study, we hypothesized that exercise-induced acceleration of myocardial tissue oxygenation recovery contributes to this protection. C57BL/6 mice (4 weeks old) were trained on treadmills for 45 min/day at a treading rate of 15 m/min for 8 weeks. At the end of 8-week exercise training, mice underwent 30-min left anterior descending coronary artery occlusion followed by 60-min or 24-h reperfusion. Electron paramagnetic resonance oximetry was performed to measure myocardial tissue oxygenation. Western immunoblotting analyses, gene transfection, and myography were examined. The oximetry study demonstrated that exercise markedly shortened myocardial tissue oxygenation recovery time following reperfusion. Exercise training up-regulated Kir6.1 protein expression (a subunit of ATP-sensitive K(+)channel on vascular smooth muscle cells, VSMC sarc-K(ATP)) and protected the heart from I/R injury. In vivo gene transfer of dominant negative Kir6.1AAA prolonged the recovery time and enlarged infarct size. In addition, transfection of Kir6.1AAA increased the stiffness and reduced the relaxation capacity in the vasculature. Together, our study demonstrated that exercise training up-regulated Kir6.1, improved tissue oxygenation recovery, and protected the heart against I/R injury. This exercise-induced cardioprotective mechanism may provide a potential therapeutic intervention targeting VSMC sarc-K(ATP) channels and reperfusion recovery

    Acanthopagrus latus migration patterns and habitat use in Wanshan Islands, Pearl River Estuary, determined using otolith microchemical analysis

    Get PDF
    IntroductionThe waters surrounding the Wanshan Islands are important traditional fishing grounds in China, with rich habitat types. Acanthopagrus latus is an economically important species in this area; however, the distribution of its spawning grounds and habitat use patterns remain unknown.MethodsThus 100 otolith samples of A. latus were collected from three geographic areas (MW: Qi’ao Island Mangrove Water Habitat; OW: Yamen Estuary Oyster Farm Water Habitat; RW: Dong’ao-Guishan Island Reef Water Habitat), and the concentrations of Sr and Ca along the shortest axis of the vertical otolith annual or lunar rings were measured to span the entire life cycle of A. latus, with the core and edge areas corresponding to environmental characteristics at birth and capture, respectively.Results and discussionAnalysis of covariance (ANCOVA) revealed that the ratios of Sr/Ca in otolith edges of RW samples are significantly higher than those of OW and MW samples; however, both the values of Sr/Ca ratio in otolith cores collected from OW and MW are comparable with those of RW samples. Cluster analysis and non-metric multidimensional scaling (nMDS) indicated that at the juvenile stage, RW and MW individuals in the two main clusters belonged to the same cluster. There was no significant difference between the cores of the RW samples and the edges of the MW and OW samples. Therefore, the spawning area of A. latus in the Wanshan Islands is thought to have originated from low to medium-salinity waters with mangroves and oyster farm habitats in the Pearl River Estuary. A. latus from RW was found to have three distinct habitat-use patterns: 1) Marine Resident (7.2% of sampled fish) fish that remain in marine habitats for life; 2) Marine Migrant (16.4% of sampled fish) juveniles inhabit low to moderate salinity habitats and migrate to marine habitats as they grow; 3) Estuarine Visitor (76.4% of sampled fish) repeated migration between low to moderate salinity and marine habitats. This suggests widespread migration between estuarine and marine habitats throughout the ontogeny. The plasticity of this habitat use and the protection of spawning grounds should be considered in future fisheries management because A. Latus in this area has been the victim of the overexploitation of resources

    3D DYNAMIC TIME-HISTORY RESPONSE ANALYSIS OF AN ISLAND PLATFORM METRO STATION IN LOESS AREA

    No full text
    Through the years, the seismic resistance of underground structures has attracted more and more attention, and dynamic characteristics of metro station is one of the most important issues. In this article, the 3D numerical model of Zhang Wangqu metro station along Metro Line 5 in Xi'an is established to study on seismic dynamic response of roof, floor, columns and beams in the island platform metro station. Compared with the earthquake damage of Dakai metro station in the Kobe M7.2 Earthquake and the shaking table test of metro station in loess area, results reveal that horizontal acceleration can reflect seismic wave characteristics under the horizontal seismic wave; the maximum relative displacement of roof and floor, the maximum axle force and shear force at transfer node are bigger than the standard section and reduce with the increase of buried depth; the maximum axle force and shear force of columns increases from top to bottom. The island platform metro station should focus on the structural settings of transfer node, and the columns and beams here must select materials with greater strength

    Layered sphere-shaped TiO2 capped with gold nanoparticles on structural defects and their catalysis of formaldehyde oxidation

    No full text
    We describe here a one-step method for the synthesis of Au/TiO2 nanosphere materials, which were formed by layered deposition of multiple anatase TiO2 nanosheets. The Au nanoparticles were stabilized by structural defects in each TiO2 nanosheet, including crystal steps and edges, thereby fixing the Au-TiO2 perimeter interface. Reactant transfer occurred along the gaps between these TiO2 nanosheet layers and in contact with catalytically active sites at the Au-TiO2 interface. The doped Au induced the formation of oxygen vacancies in the Au-TiO2 interface. Such vacancies are essential for generating active oxygen species (*O-) on the TiO2 surface and Ti3+ ions in bulk TiO2. These ions can then form Ti3+-O-Ti4+ species, which are known to enhance the catalytic activity of formaldehyde (HCHO) oxidation. These studies on structural and oxygen vacancy defects in Au/TiO2 samples provide a theoretical foundation for the catalytic mechanism of HCHO oxidation on oxide-supported Au materials. (C) 2015 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V

    Green synthesis of Ag nanoparticles using elm pod polysaccharide for catalysis and bacteriostasis

    No full text
    The green synthesis of silver nanoparticles (Ag NPs) for catalysis and biological applications has gained great interest. Natural elm pods are a type of food that possesses anti-inflammatory and pain-relieving effects. In this study, elm pod polysaccharide (EPP) was extracted from elm pods using hot water extraction for the first time. Biocompatible EPP-stabilized silver nanoparticles (EPP-Agn NPs) were prepared by using a green synthesis method. The EPP-Ag25 NPs had a hydrodynamic size of 40.9 nm and a highly negative surface charge of −27.4 mV. Furthermore, EPP-Ag25 NPs exhibited high catalytic activity for the reduction of 4-nitrophenol, and the catalytic reaction followed a pseudo-first order kinetic equation. More importantly, the inhibition rate of EPP-Ag25 NPs on Escherichia coli was 71 % when samples were treated with an 808 nm laser. Besides, EPP-Agn NPs effectively inhibited the proliferation of tumor cells irradiated by an 808 nm laser. The improved performance of EPP-Agn NPs was due to the good stability of EPP. Taken together, EPP-Agn NPs had good stability, catalytic activity, antibacterial and antitumor ability under laser irradiation. EPP is a good stabilizer for many nanoparticles which have broad applications in the field of catalysis and biomedicine in the future.</p

    Application Value of CTA in the Computer-Aided Diagnosis of Subarachnoid Hemorrhage of Different Origins

    No full text
    Subarachnoid hemorrhage (SAH) is difficult to detect because of its circulation through subarachnoid space, which leads to a high rate of missed diagnosis. Based on the above background, the purpose of this study is to study the application value of brain CT angiography (CTA) in computer-aided diagnosis of subarachnoid hemorrhage with a wide range of brain digital subtraction angiography as a gold standard. This paper collected images and related medical records of 111 patients with spontaneous subarachnoid hemorrhage receiving brain CTA and DSA examinations from February 2015 to November 2019 in the neurology department of our hospital. In contrast to the number, position, length, width, and neck width of the causative aneurysm detected by DSA, we evaluated the diagnostic results of CTA and evaluated whether there was statistical difference between the two detectives of intracranial aneurysms. The results showed that the area under ROC curve of subtraction CTA and conventional CTA was 1.000 and 0.818, respectively, which indicated that the former had better display effect on internal carotid aneurysm (AUC > 0.9), while the latter had medium value (0.7 < AUC ≤ 0.9), and the difference was statistically significant (z = 2.390, p=0.017)
    corecore